| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4717656 | F | Antiarrhythmic activity in 50 Hz sinusoidal alternating current-induced guinea pig left atrium arrhythmias model assessed as increase in threshold of ac-arrhythmia at 1 x 10^-5 M measured for every 30 mins relative to control | Cavia porcellus | 2 | tissue-based format | Scientific Literature | ||
| 2. | ALA4717658 | F | Antiarrhythmic activity in 50 Hz sinusoidal alternating current-induced guinea pig left atrium arrhythmias model assessed as increase in threshold of ac-arrhythmia measured for every 30 mins relative to control | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 3. | ALA4717659 | A | Negative inotropic activity in guinea pig left atrium assessed as decrease in 1 Hz driven developed tension at 1 x 10^-5 M relative to control | Cavia porcellus | 2 | tissue-based format | Scientific Literature | ||
| 4. | ALA4717663 | A | Negative inotropic activity in guinea pig left atrium assessed as decrease in 1 Hz driven developed tension | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 5. | ALA4717664 | A | Negative inotropic activity in guinea pig spontaneously beating right atrium assessed as decrease in developed tension at 5 x 10^-6 M relative to control | Cavia porcellus | 2 | tissue-based format | Scientific Literature | ||
| 6. | ALA4717666 | A | Negative inotropic activity in guinea pig spontaneously beating right atrium assessed as decrease in developed tension | Cavia porcellus | 3 | tissue-based format | Scientific Literature | ||
| 7. | ALA4717667 | A | Negative chronotropic activity in guinea pig spontaneously beating right atrium assessed as decrease in atrial rate at 1 x 10^-5 M relative to control | Cavia porcellus | 3 | tissue-based format | Scientific Literature | ||
| 8. | ALA4717671 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig aortic strips at 1 x 10^-4 M relative to control | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 9. | ALA4717673 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig longitudinal smooth muscle at 5 x 10^-5 M relative to control | Cavia porcellus | 1 | tissue-based format | Scientific Literature | ||
| 10. | ALA4717675 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig longitudinal smooth muscle | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 11. | ALA4717676 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 25 mg/kg, ip measured after 30 mins by rotarod test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 12. | ALA4717677 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 25 mg/kg, ip measured after 45 mins by rotarod test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 13. | ALA4717678 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 25 mg/kg, ip measured after 60 mins by rotarod test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 14. | ALA4717679 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 50 mg/kg, ip measured after 30 mins by rotarod test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA4717680 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 50 mg/kg, ip measured after 45 mins by rotarod test | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 16. | ALA4717681 | T | Toxicity in mouse assessed as motor coordination impairment by measuring number of falls from rotarod at 50 mg/kg, ip measured after 60 mins by rotarod test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA4717682 | A | Cytotoxicity against human HepG2 cells at EC50 concentration incubated for 2 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4717683 | A | Cytotoxicity against human HepG2 cells at 10 times of EC50 concentration incubated for 2 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4717684 | A | Binding affinity to P-gp in dog MDCK-MDR1 cells using calcein-AM as substrate at 100 uM after 30 mins by fluorescence analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4809520 | F | Antiarrhythmic activity in patient-derived hiPSC-CMs carrying LQT3 mutation assessed as cessation dose for cell beating | Homo sapiens | 61 | tissue-based format | Scientific Literature |
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