| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4729958 | Functional | Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity assay | Homo sapiens | 19 | ALA4725391 | cell-based format | Scientific Literature | |
| 2. | ALA4729959 | Physicochemical | Octanol-water distribution coefficient, log D of the compound by shake flask method | 12 | ALA4725391 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA4729961 | ADME | Permeability of compound by PAMPA assay | 19 | ALA4725391 | assay format | Scientific Literature | ||
| 4. | ALA4729965 | ADME | Oral bioavailability in C57BL/6 mouse measured after 0.25 to 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | ALA4725391 | organism-based format | Scientific Literature | |
| 5. | ALA4729967 | ADME | Dose normalized AUC in C57BL/6 mouse at 3 mg/kg, po measured after 0.25 to 24 hrs by LC-MS/MS analysis | Mus musculus | 6 | ALA4725391 | organism-based format | Scientific Literature | |
| 6. | ALA4729969 | ADME | Clearance in C57BL/6 mouse at 1 mg/kg, iv administered as bolus dose measured after 0.083 to 24 hrs by LC-MS/MS analysis | Mus musculus | 8 | ALA4725391 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!