# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4675306 | Binding | Displacement of [3H]diprenorphine from human DOR expressed in CHO cell membranes incubated for 60 mins liquid scintillation counting assay | Homo sapiens | 44 | ALA4673223 | cell membrane format | Scientific Literature | |
2. | ALA4675307 | Binding | Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method | Rattus norvegicus | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
3. | ALA4675308 | Binding | Displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method | Rattus norvegicus | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
4. | ALA4675309 | Binding | Displacement of [3H]U69,593 from kappa opioid receptor in guinea-pig brain membranes incubated for 30 mins by liquid scintillation counting method | Cavia porcellus | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
5. | ALA4675310 | Binding | Selectivity index, ratio of Ki for displacement of [3H][Ile5,6]deltorphin II from delta opioid receptor in rat brain membranes to Ki for displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes | Rattus norvegicus | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
6. | ALA4675311 | Binding | Selectivity index, ratio of Ki for displacement of [3H]U69,593 from kappa opioid receptor in guinea-pig brain membranes to Ki for displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes | 42 | ALA4673223 | cell membrane format | Scientific Literature | ||
7. | ALA4675312 | Binding | Agonist activity at human MOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
8. | ALA4675313 | Binding | Agonist activity at human DOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
9. | ALA4675314 | Binding | Agonist activity at human MOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay relative to DAMGO | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
10. | ALA4675315 | Binding | Agonist activity at human DOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay relative to DPDPE | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
11. | ALA4675316 | Binding | Agonist activity at human KOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
12. | ALA4675317 | Binding | Agonist activity at human KOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay relative to U69,593 | Homo sapiens | 42 | ALA4673223 | cell membrane format | Scientific Literature | |
13. | ALA4675319 | Functional | Antinociceptive activity in CD1 mouse assessed as inhibition of the writhing response at 50 ug/kg, sc and co-administered with 1 mg/kg naloxone methiodide and measured after 30 mins post dose by acetic acid-induced writhing assay | Mus musculus | 4 | ALA4673223 | organism-based format | Scientific Literature |