# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4734202 | Binding | Displacement of [3H]-pentazocine from sigma1 receptor in guinea pig brain membrane incubated for 120 mins by liquid scintillation counting method | Cavia porcellus | 19 | ALA4732089 | cell membrane format | Scientific Literature | |
2. | ALA4734204 | Binding | Displacement of [3H]-MK-801 from NMDA receptor PCP binding site in pig brain cortex at 1 uM incubated for 150 mins by liquid scintillation counting method relative to control | Sus scrofa | 12 | ALA4732089 | tissue-based format | Scientific Literature | |
3. | ALA4734205 | Binding | Agonist activity at sigma1 receptor in rat PC12 cells assessed as reduction in KCl-induced Ca2+ influx at 10 nM measured after 30 mins by Fura2AM dye based fluorescence microscopic analysis | Rattus norvegicus | 3 | ALA4732089 | cell-based format | Scientific Literature | |
4. | ALA4734206 | Binding | Antagonist activity at sigma1 receptor in rat PC12 cells assessed as reduction in opipramol activity by measuring increase in Ca2+-influx at 10 nM measured after 30 mins in presence of KCl by Fura2AM dye based fluorescence microscopic analysis relative to control | Rattus norvegicus | 3 | ALA4732089 | cell-based format | Scientific Literature | |
5. | ALA4734218 | Binding | Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method relative to control | Rattus norvegicus | 14 | ALA4732089 | cell membrane format | Scientific Literature |