# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700945 | Functional | Activation of human GPR10 overexpressed in CHO-K1 cells assessed as increase in beta arrestin recruitment incubated for 90 mins in presence of 10% FBS by PathHunter assay | Homo sapiens | 9 | ALA4699444 | cell-based format | Scientific Literature | |
2. | ALA4700946 | Functional | Ratio of EC50 for activation of human GPR10 overexpressed in CHO-K1 cells assessed as increase in beta arrestin recruitment incubated for 90 mins in presence of 10% FBS by PathHunter assay to EC50 for activation of human GPR10 overexpressed in CHO-K1 cells assessed as increase in beta arrestin recruitment incubated for 90 mins by PathHunter assay | Homo sapiens | 9 | ALA4699444 | cell-based format | Scientific Literature | |
3. | ALA4700947 | ADME | Activation of human NPFF2R overexpressing CHO cells assessed as inhibition of forskolin-stimulated cAMP degradation incubated for 30 mins in presence of IBMX and 10% FBS by fluorescence based assay | Homo sapiens | 9 | ALA4699444 | cell-based format | Scientific Literature | |
4. | ALA4700948 | ADME | Activation of human NPFF2R overexpressing CHO cells assessed as inhibition of forskolin-stimulated cAMP degradation incubated for 30 mins in presence of IBMX by fluorescence based assay | Homo sapiens | 9 | ALA4699444 | cell-based format | Scientific Literature | |
5. | ALA4700949 | Unassigned | Ratio of EC50 for activation of human NPFF2R overexpressing CHO cells assessed as inhibition of forskolin-stimulated cAMP degradation incubated for 30 mins in presence of IBMX and 10% FBS by fluorescence based assay to EC50 for activation of human GPR10 overexpressed in CHO-K1 cells assessed as increase in beta arrestin recruitment incubated for 90 mins by PathHunter assay | 9 | ALA4699444 | cell-based format | Scientific Literature | ||
6. | ALA4700961 | Functional | Activation of human GPR10 overexpressed in CHO-K1 cells assessed as increase in beta arrestin recruitment incubated for 90 mins by PathHunter assay | Homo sapiens | 122 | ALA4699444 | cell-based format | Scientific Literature |