| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4709468 | Binding | Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK1 expressed in sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay | Homo sapiens | 24 | ALA4706541 | cell-based format | Scientific Literature | |
| 2. | ALA4709469 | Binding | Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK4 expressed in baculovirus infected sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay | Homo sapiens | 6 | ALA4706541 | cell-based format | Scientific Literature | |
| 3. | ALA4709470 | Binding | Selectivity index ratio of IC50 for inhibition of human PAK4 to IC50 for human PAK1 | Homo sapiens | 6 | ALA4706541 | assay format | Scientific Literature | |
| 4. | ALA4709471 | Binding | Inhibition of human ERG | Homo sapiens | 7 | ALA4706541 | single protein format | Scientific Literature | |
| 5. | ALA4709501 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition at 1 uM after 72 hrs by Cell Titer-Glo assay relative to control | Homo sapiens | 15 | ALA4706541 | cell-based format | Scientific Literature | |
| 6. | ALA4709502 | Functional | Antiproliferative activity against human HCT-116 cells assessed as growth inhibition at 1 uM after 72 hrs by Cell Titer-Glo assay relative to control | Homo sapiens | 15 | ALA4706541 | cell-based format | Scientific Literature |
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