# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4707889 | Functional | Cytotoxicity against human EC-109 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4706492 | cell-based format | Scientific Literature | |
2. | ALA4707890 | Binding | Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21 (DE) cells at 20 uM using H3K4me2 substrate incubated for 30 mins by amplex red assay relative to control | Homo sapiens | 28 | ALA4706492 | cell-based format | Scientific Literature | |
3. | ALA4707891 | Binding | Inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21 (DE) cells using H3K4me2 substrate incubated for 30 mins by amplex red assay | Homo sapiens | 5 | ALA4706492 | cell-based format | Scientific Literature | |
4. | ALA4707892 | Binding | Potency index, ratio of TCP IC50 to test compound IC50 for inhibition of recombinant human LSD1 (157 to 852 residues) expressed in Escherichia coli BL21 (DE) cells | Homo sapiens | 1 | ALA4706492 | cell-based format | Scientific Literature | |
5. | ALA4707893 | Binding | Inhibition of LSD1 in human MGC803 assessed as reduction in H3K4me2 protein expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706492 | tissue-based format | Scientific Literature | |
6. | ALA4707894 | Binding | Inhibition of MAO-A (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
7. | ALA4707895 | Binding | Inhibition of MAO-B (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
8. | ALA4707896 | Binding | Inhibition of CDK1 (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
9. | ALA4707897 | Binding | Inhibition of CDK2 (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
10. | ALA4707898 | Binding | Inhibition of CDK6 (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
11. | ALA4707899 | Binding | Inhibition of BTK (unknown origin) at 20 uM relative to control | Homo sapiens | 1 | ALA4706492 | single protein format | Scientific Literature | |
12. | ALA4707900 | Functional | Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4706492 | cell-based format | Scientific Literature | |
13. | ALA4707901 | Functional | Cytotoxicity against human PC-3 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4706492 | cell-based format | Scientific Literature | |
14. | ALA4707902 | Functional | Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Mus musculus | 5 | ALA4706492 | cell-based format | Scientific Literature |