In vivo inhibition of GOAT in C57BL/6 mouse assessed as reduction in ratio of AG to total-ghrelin at 0.3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as increase in unacylated-ghrelin level at 10 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as increase in unacylated-ghrelin level at 3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as increase in unacylated-ghrelin level at 1 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as increase in unacylated-ghrelin level at 0.3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as decrease in plasma acylated ghrelin level at 10 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as decrease in plasma acylated ghrelin level at 3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as decrease in plasma acylated ghrelin level at 1 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as decrease in plasma acylated ghrelin level at 0.3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate incubated for 1 hr by ELISA
In vivo inhibition of GOAT in C57BL/6 mouse assessed as reduction in ratio of AG to total-ghrelin at 10 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as reduction in ratio of AG to total-ghrelin at 3 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control
In vivo inhibition of GOAT in C57BL/6 mouse assessed as reduction in ratio of AG to total-ghrelin at 1 mg/kg, po BID administered via gavage for 3 days by ELISA relative to control