| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4678399 | B | Inhibition of human cathepsin B using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measured for 5 mins by fluorescence assay | Homo sapiens | 19 | ALA4673336 | single protein format | Scientific Literature | |
| 2. | ALA4678400 | B | Inhibition of recombinant human cathepsin K using Z-Leu-Arg-AMC as substrate measured after 20 mins | Homo sapiens | 19 | ALA4673336 | single protein format | Scientific Literature | |
| 3. | ALA4678401 | B | Inhibition of human cathepsin L | Homo sapiens | 19 | ALA4673336 | single protein format | Scientific Literature | |
| 4. | ALA4678402 | B | Inhibition of human cathepsin S | Homo sapiens | 19 | ALA4673336 | single protein format | Scientific Literature | |
| 5. | ALA4678403 | B | Inhibition of human cathepsin B at 10 uM using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measured for 5 mins by fluorescence assay relative to control | Homo sapiens | 1 | ALA4673336 | single protein format | Scientific Literature | |
| 6. | ALA4678404 | B | Inhibition of recombinant human cathepsin K at 10 uM using Z-Leu-Arg-AMC as substrate measured after 20 mins relative to control | Homo sapiens | 6 | ALA4673336 | single protein format | Scientific Literature | |
| 7. | ALA4678405 | B | Inhibition of human cathepsin L at 10 uM relative to control | Homo sapiens | 4 | ALA4673336 | single protein format | Scientific Literature | |
| 8. | ALA4678409 | B | Selectivity index, ratio of pKi for human cathepsin S to pKi for human cathepsin B using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measured for 5 mins by fluorescence assay | Homo sapiens | 1 | ALA4673336 | assay format | Scientific Literature | |
| 9. | ALA4678410 | B | Selectivity index, ratio of pKi for human cathepsin S to pKi for recombinant human cathepsin K using Z-Leu-Arg-AMC as substrate measured after 20 mins | Homo sapiens | 1 | ALA4673336 | protein format | Scientific Literature | |
| 10. | ALA4678411 | B | Selectivity index, ratio of pKi for human cathepsin S to pKi for human cathepsin L | Homo sapiens | 1 | ALA4673336 | assay format | Scientific Literature |
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