| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4714828 | Binding | Inhibition of recombinant human His-tagged FGFR4 (781 to 1338 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 peptide as substrate incubated for 1 hr in presence of ATP by Z'-LYTE assay | Homo sapiens | 12 | ALA4706732 | assay format | Scientific Literature | |
| 2. | ALA4714829 | ADME | Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 01 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay | Homo sapiens | 12 | ALA4706732 | assay format | Scientific Literature | |
| 3. | ALA4714830 | ADME | Inhibition of recombinant human His-tagged FGFR2 (403 to 822 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 peptide as substrate after 1 hr in presence of ATP by Z'-LYTE assay | Homo sapiens | 12 | ALA4706732 | assay format | Scientific Literature | |
| 4. | ALA4714831 | ADME | Inhibition of recombinant human His-tagged FGFR3 (399 to 806 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 04 peptide as substrate after 1 hr in presence of ATP by Z'-LYTE assay | Homo sapiens | 12 | ALA4706732 | assay format | Scientific Literature | |
| 5. | ALA4714838 | Binding | Reversible covalent binding affinity to FGFR4 (unknown origin) assessed as restoration of kinase activiy at 8 uM preincubated for 120 mins followed by dialysis of protein adduct for 2 days by MALDI-TOF MS analysis | Homo sapiens | 1 | ALA4706732 | single protein format | Scientific Literature | |
| 6. | ALA4714839 | Functional | Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 5 | ALA4706732 | cell-based format | Scientific Literature | |
| 7. | ALA4714840 | Functional | Antiproliferative activity against human MDA-MB-453 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 5 | ALA4706732 | cell-based format | Scientific Literature | |
| 8. | ALA4714841 | ADME | Antiproliferative activity against human H1299 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 5 | ALA4706732 | cell-based format | Scientific Literature |
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