# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4734514 | ADME | Cytotoxicity against mouse L5178Y cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Mus musculus | 28 | ALA4732098 | cell-based format | Scientific Literature | |
2. | ALA4734515 | ADME | Cytotoxicity against mouse L5178Y cells transfected with human ABCB1 assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Mus musculus | 28 | ALA4732098 | cell-based format | Scientific Literature | |
3. | ALA4734516 | ADME | Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 28 | ALA4732098 | cell-based format | Scientific Literature | |
4. | ALA4734517 | ADME | Cytotoxicity against human COLO 320 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Homo sapiens | 28 | ALA4732098 | cell-based format | Scientific Literature | |
5. | ALA4734518 | Binding | Inhibition of human ABCB1 expressed in mouse L5178Y-MDR cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry | Homo sapiens | 28 | ALA4732098 | cell-based format | Scientific Literature | |
6. | ALA4734519 | Binding | Inhibition of human ABCB1 expressed in mouse L5178Y-MDR cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 20 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry | Homo sapiens | 29 | ALA4732098 | cell-based format | Scientific Literature | |
7. | ALA4734520 | Binding | Inhibition of ABCB1 in human resistant COLO 320 cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry | Homo sapiens | 28 | ALA4732098 | tissue-based format | Scientific Literature | |
8. | ALA4734521 | Binding | Inhibition of ABCB1 in human resistant COLO 320 cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 20 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry | Homo sapiens | 29 | ALA4732098 | tissue-based format | Scientific Literature |