# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4718732 | ADME | Cytotoxicity against rat L6 cells assessed as reduction in cell viability by alamar blue dye based fluorimetry analysis | Rattus norvegicus | 19 | ALA4715756 | cell-based format | Scientific Literature | |
2. | ALA4718733 | Toxicity | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Leishmania donovani MHOM/ET/67/L82 | 18 | ALA4715756 | assay format | Scientific Literature | ||
3. | ALA4718734 | Functional | Antiprotozoal activity against Leishmania donovani MHOM/ET/67/L82 alamar blue staining-based fluorometric analysis | Leishmania donovani | 20 | ALA4715756 | organism-based format | Scientific Literature | |
4. | ALA4718735 | Toxicity | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma cruzi Tulahuen C4 | 19 | ALA4715756 | assay format | Scientific Literature | ||
5. | ALA4718736 | Functional | Trypanocidal activity against Trypanosoma cruzi Tulahuen C4 amastigotes intra-peritoneally infected in BALB/C mouse assessed as reduction in spleen trypomastigotes treated day 4 postinfection for 20 days | Trypanosoma cruzi | 20 | ALA4715756 | organism-based format | Scientific Literature | |
6. | ALA4718737 | Toxicity | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma brucei rhodesiense STIB900 trypomastigotes | 19 | ALA4715756 | assay format | Scientific Literature | ||
7. | ALA4718738 | Functional | Antiprotozoal activity against Trypanosoma brucei rhodesiense STIB900 trypomastigotes by alamar blue staining-based fluorometric analysis | Trypanosoma brucei rhodesiense | 20 | ALA4715756 | organism-based format | Scientific Literature |