# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701282 | Binding | Inhibition of tracer 236 binding to recombinant human GST-tagged TNK2 (110 to 476 residues) expressed in baculovirus expression system incubated for 60 mins by by Lanthascreen assay | Homo sapiens | 24 | ALA4699457 | assay format | Scientific Literature | |
2. | ALA4701283 | Binding | Inhibition of TNK2 D163E mutant in mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer glo luminescent cell viability assay | Mus musculus | 24 | ALA4699457 | cell-based format | Scientific Literature | |
3. | ALA4701284 | ADME | Cytotoxicity against mouse BaF3 cells assessed as reduction in cell viability incubated for 72 hrs by cell titer glo luminescent cell viability assay | Mus musculus | 24 | ALA4699457 | cell-based format | Scientific Literature | |
4. | ALA4701287 | ADME | AUC (0 to infinity) in CD-1 mouse at 10 mg/kg, po | Mus musculus | 3 | ALA4699457 | organism-based format | Scientific Literature | |
5. | ALA4701288 | ADME | Oral bioavailability in CD-1 mouse at 10 mg/kg | Mus musculus | 3 | ALA4699457 | organism-based format | Scientific Literature | |
6. | ALA4701289 | ADME | Clearance in CD-1 mouse at 3 mg/kg, iv | Mus musculus | 3 | ALA4699457 | organism-based format | Scientific Literature | |
7. | ALA4701290 | ADME | Half life in CD-1 mouse at 3 mg/kg, iv | Mus musculus | 3 | ALA4699457 | organism-based format | Scientific Literature |