# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4709557 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 0.01 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature | |
2. | ALA4709558 | Binding | Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction | Homo sapiens | 25 | ALA4706544 | protein format | Scientific Literature | |
3. | ALA4709560 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 0.1 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature | |
4. | ALA4709561 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 1 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature | |
5. | ALA4709562 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 5 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature | |
6. | ALA4709563 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 10 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature | |
7. | ALA4709564 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in human HepG2 cells transfected with ARE-C8 assessed as activation of Nrf2-ARE transcriptional activity at 20 uM after 12 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 25 | ALA4706544 | cell-based format | Scientific Literature |