| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4668685 | B | Inhibition of human CD73 expressed in CHO cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 58 | cell-based format | Scientific Literature | ||
| 2. | ALA4668686 | A | Clearance in Sprague-Dawley rat at 0.5 mg/kg, iv | Rattus norvegicus | 18 | organism-based format | Scientific Literature | ||
| 3. | ALA4668687 | B | Inhibition of soluble human CD73 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA4668688 | B | Inhibition of CD73 in human CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4668689 | B | Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColorLock gold reagent based colorimetric assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4668690 | B | Inhibition of CD73 in human PBMC using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2.5 hrs by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 7. | ALA4668691 | B | Inhibition of CD39 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4668692 | B | Inhibition of NTPDase 2 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4668693 | B | Inhibition of NTPDase 3 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4668694 | B | Inhibition of NTPDase 8 (unknown origin) expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 mins by PiColorLock gold reagent based colorimetric assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4668696 | A | Clearance in mouse at 0.5 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA4668697 | A | Volume of distribution at steady state in mouse at 0.5 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA4668698 | A | Half life in mouse at 0.5 mg/kg, iv | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA4668699 | A | Fraction unbound in mouse plasma | Mus musculus | 3 | cell-free format | Scientific Literature | ||
| 15. | ALA4668700 | A | Volume of distribution at steady state in Sprague-Dawley rat at 0.5 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4668701 | A | Half life in Sprague-Dawley rat at 0.5 mg/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4668702 | A | Fraction unbound in Sprague-Dawley rat plasma | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 18. | ALA4668703 | A | Clearance in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA4668704 | A | Volume of distribution at steady state in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA4668705 | A | Half life in dog at 0.5 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!