| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4704893 | B | Agonist activity at GAL4-tagged PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation at 5 uM incubated for 16 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA4704894 | B | Agonist activity at GAL4-tagged PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4704895 | B | Agonist activity at GAL4-tagged PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation at 5 uM incubated for 16 hrs by luciferase reporter gene assay relative to rosiglitazone | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4704896 | B | Agonist activity at GAL4-tagged PPARalpha-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation at 1 uM incubated for 16 hrs by luciferase reporter gene assay relative to GW7647 | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4704897 | B | Agonist activity at GAL4-tagged PPARalpha-LBD (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4704898 | T | Toxicity in HEK293 cells assessed as effect on ATP content at 0.1 uM to 10000 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4704899 | B | Agonist activity at PPARg (unknown origin) expressed in HEK293 cells assessed as induction of receptor transactivation at 1 uM incubated for 17 hrs by PPRE-driven luciferase reporter gene assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4704901 | B | Binding affinity to PPARg (unknown origin) assessed as association constant by SPR assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4704902 | B | Binding affinity to PPARa (unknown origin) assessed as association constant by SPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4704903 | B | Binding affinity to PPARg (unknown origin) assessed as dissociation constant by SPR assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4704904 | B | Binding affinity to PPARa (unknown origin) assessed as dissociation constant by SPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4704905 | B | Binding affinity to PPARg (unknown origin) by SPR assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4704906 | B | Binding affinity to PPARa (unknown origin) by SPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4704907 | B | Induction of PPARg-LBD/GAL4-tagged RXRa (unknown origin) heterodimerization expressed in HEK293 cells at 0.01 to 10 uM incubated for 16 hrs by luciferase reporter gene based mammalian two hybrid assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4704908 | B | Agonist activity at GAL4-tagged RXRa-LBD (unknown origin) expressed in HEK293 cells at 0.01 to 10 uM incubated for 16 hrs by RXRE-based luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4704909 | B | Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as displacement of NCoR incubated for 16 hrs by luciferase reporter gene based mammalian two hybrid assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4704910 | B | Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as displacement of SMRT incubated for 16 hrs by luciferase reporter gene based mammalian two hybrid assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4704911 | B | Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as recruitment of TIF2 incubated for 16 hrs by luciferase reporter gene based mammalian two hybrid assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4704912 | B | Agonist activity at PPARg-LBD (unknown origin) expressed in HEK293 cells assessed as recruitment of MED1 incubated for 16 hrs by luciferase reporter gene based mammalian two hybrid assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4704913 | B | Binding affinity to PPARg (unknown origin) assessed as reduction in CDK5-mediated phosphorylation of PPARg serine 273 residue at 0.1 uM incubated for 3.5 hrs by ELISA | Homo sapiens | 2 | cell-based format | Scientific Literature |
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