| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4730887 | F | Cytotoxicity against human CA46 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA4730888 | B | Inhibition of IKKalpha/IKKbeta in human HEK293T cells transfected with firefly luciferase gene assessed as inhibition of TNF-alpha-stimulated NF-kappaB signalling preincubated for 1 hr followed by TNF alpha stimulation measured after 3 hrs by luciferase reporter gene assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 3. | ALA4730889 | A | Cytotoxicity against human HEK293T cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 4. | ALA4730890 | A | Cytotoxicity against human Hs578Bst cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 5. | ALA4730891 | A | Cytotoxicity against human Hs888Lu cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 6. | ALA4730892 | A | Cytotoxicity against human Hs895SK cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 7. | ALA4730893 | F | Cytotoxicity against human Hs895T cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 8. | ALA4730894 | F | Cytotoxicity against human Hs-578T cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 9. | ALA4730895 | F | Cytotoxicity against human PSN1 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 10. | ALA4730896 | F | Cytotoxicity against human HCC1599 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 11. | ALA4730897 | F | Cytotoxicity against human RC-K8 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 12. | ALA4730898 | F | Cytotoxicity against human SU-DHL-4 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 13. | ALA4730899 | F | Cytotoxicity against human NCI-H446 cells assessed as reduction in cell viability measured after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 14. | ALA4730900 | B | Inhibition of IKKbeta in human HeLa cells assessed as reduction in IL-1 beta-stimulated IKK beta nuclear translocation at 10 uM pretreated with compound for 4 hrs followed by stimulation with IL-1 beta for 1 hr by immunohistochemical staining/confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4730901 | T | Selectivity index, ratio of IC50 for human Hs578Bst cells to EC50 for human RC-K8 cells measured after 24 hrs by CellTiter-Glo luminescent assay | 1 | assay format | Scientific Literature | |||
| 16. | ALA4730902 | B | Inhibition of IKKalpha/IKKbeta in human HEK293T cells transfected with firefly luciferase gene assessed as inhibition of NF-kappaB signalling at 10 uM by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4730907 | B | Inhibition of IKKalpha/IKKbeta in human HEK293T cells transfected with firefly luciferase gene assessed as inhibition of IL-1 beta-stimulated NF-kappaB signalling preincubated for 1 hr followed by IL-1 beta stimulation measured after 3 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4730908 | B | Inhibition of JRA-031 binding to IKKalpha in TNF-alpha-stimulated human HEK293T cells at 1 uM pretreated with compound for 1 hr followed by labeling with JRA-031 for 1 hr followed by stimulation with TNF-alpha for 1 hr by pull down based mass spectrometry | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 19. | ALA4730909 | B | Inhibition of JRA-031 binding to IKKbeta in TNF-alpha-stimulated human HEK293T cells at 1 uM pretreated with compound for 1 hr followed by labeling with JRA-031 for 1 hr followed by stimulation with TNF-alpha for 1 hr by pull down based mass spectrometry | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 20. | ALA4730912 | B | Inhibition of IKKalpha in human HeLa cells assessed as reduction in IL-1 beta-stimulated IKK alpha nuclear translocation at 10 uM pretreated with compound for 4 hrs followed by stimulation with IL-1 beta for 1 hr by immunohistochemical staining/confocal microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature |
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