| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4676489 | Binding | Inhibition of human coagulation factor alpha thrombin in presence of Boc-Val-Pro-Arg-AMC as fluorogenic substrate at 1 uM measured at 1 min interval for 1 hr by fluorometric assay relative to control | Homo sapiens | 25 | ALA4673255 | single protein format | Scientific Literature | |
| 2. | ALA4676490 | Binding | Inhibition of human coagulation factor XIIA in presence of Boc-Gln-Gly-Arg-AMC as fluorogenic substrate at 1 uM measured at 1 min interval for 1 hr by fluorometric assay relative to control | Homo sapiens | 25 | ALA4673255 | single protein format | Scientific Literature | |
| 3. | ALA4676500 | Functional | Anticoagulant activity in human blood assessed as increase in activated partial thromboplastin time at 300 uM incubated for 1 min by aPTT reagent based assay relative to control | Homo sapiens | 25 | ALA4673255 | tissue-based format | Scientific Literature | |
| 4. | ALA4676501 | ADME | Effect on blood coagulation in human blood assessed as increase in prothrombin time at 300 uM incubated for 3 mins followed by CaCl2 addition by PT reagent based assay relative to control | Homo sapiens | 25 | ALA4673255 | tissue-based format | Scientific Literature | |
| 5. | ALA4676502 | Binding | Inhibition of porcine trypsin using Z-Gly-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assay | Sus scrofa | 34 | ALA4673255 | assay format | Scientific Literature | |
| 6. | ALA4676503 | Binding | Inhibition of human coagulation factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assay | Homo sapiens | 36 | ALA4673255 | single protein format | Scientific Literature | |
| 7. | ALA4676504 | Binding | Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assay | Homo sapiens | 35 | ALA4673255 | single protein format | Scientific Literature | |
| 8. | ALA4676505 | Binding | Inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assay | Homo sapiens | 37 | ALA4673255 | single protein format | Scientific Literature |
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