# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4708408 | F | Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay | Homo sapiens | 36 | ALA4706506 | cell-based format | Scientific Literature | |
2. | ALA4708409 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay | Homo sapiens | 36 | ALA4706506 | cell-based format | Scientific Literature | |
3. | ALA4708410 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay | Homo sapiens | 36 | ALA4706506 | cell-based format | Scientific Literature | |
4. | ALA4708411 | F | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay | Homo sapiens | 36 | ALA4706506 | cell-based format | Scientific Literature | |
5. | ALA4708412 | F | Antiproliferative activity against mouse B16-F0 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK-8 assay | Mus musculus | 36 | ALA4706506 | cell-based format | Scientific Literature | |
6. | ALA4708413 | B | Inhibition of pig brain tubulin polymerization measured by light scattering based spectrophotometer method | Sus scrofa | 4 | ALA4706506 | tissue-based format | Scientific Literature | |
7. | ALA4708414 | B | Binding affinity to pig brain tubulin at 30 degree C without preincubation | Sus scrofa | 3 | ALA4706506 | tissue-based format | Scientific Literature | |
8. | ALA4708415 | B | Binding affinity to pig brain tubulin at 37 degree C without preincubation | Sus scrofa | 3 | ALA4706506 | tissue-based format | Scientific Literature | |
9. | ALA4708416 | B | Binding affinity to pig brain tubulin at 37 degree C preincubated for 5 mins | Sus scrofa | 3 | ALA4706506 | tissue-based format | Scientific Literature | |
10. | ALA4708417 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation of cells at G2/M phase measured after 48 hrs by FACS Calibur flow cytometry in relative to control | Homo sapiens | 2 | ALA4706506 | cell-based format | Scientific Literature | |
11. | ALA4708418 | F | Inhibition of cell migration in human MCF7 cells measured after 24 hrs by phase contrast microscopy based wound healing assay relative to control | Homo sapiens | 1 | ALA4706506 | cell-based format | Scientific Literature | |
12. | ALA4708420 | B | Inhibition of tubulin polymerization in mouse B16-F0 cells at 160 nM measured after 6 hrs by DAPI staining based immunofluorescent assay relative to control | Mus musculus | 1 | ALA4706506 | cell-based format | Scientific Literature | |
13. | ALA4708421 | B | Inhibition of tubulin polymerization in mouse B16-F0 cells at 40 nM measured after 6 hrs by DAPI staining based immunofluorescent assay relative to control | Mus musculus | 1 | ALA4706506 | cell-based format | Scientific Literature | |
14. | ALA4708423 | A | Metabolic stability in human liver microsomes assessed as half life in presence of NADPH at 0.5 uM measured after 4 hrs by LC/MS method | Homo sapiens | 3 | ALA4706506 | microsome format | Scientific Literature | |
15. | ALA4708424 | A | Metabolic stability in mouse liver microsomes assessed as half life in presence of NADPH at 0.5 uM measured after 4 hrs by LC/MS method | Mus musculus | 3 | ALA4706506 | microsome format | Scientific Literature | |
16. | ALA4708425 | F | Antitumour activity against mouse B16-F0 cells transplanted in C57/BL mouse assessed as decrease in tumour weight at 10 mg/kg, ip measured after 16 days in relative to control | Mus musculus | 2 | ALA4706506 | organism-based format | Scientific Literature | |
17. | ALA4708426 | F | Antitumour activity against mouse B16-F0 cells transplanted in C57/BL mouse assessed as decrease in tumour weight at 20 mg/kg, ip measured after 16 days in relative to control | Mus musculus | 1 | ALA4706506 | organism-based format | Scientific Literature | |
18. | ALA4708427 | F | Antitumour activity against mouse B16-F0 cells transplanted in C57/BL mouse assessed as decrease in tumour volume at 10 mg/kg, ip measured after 16 days in relative to control | Mus musculus | 2 | ALA4706506 | organism-based format | Scientific Literature | |
19. | ALA4708428 | F | Antitumour activity against mouse B16-F0 cells transplanted in C57/BL mouse assessed as decrease in tumour volume at 20 mg/kg, ip measured after 16 days in relative to control | Mus musculus | 1 | ALA4706506 | organism-based format | Scientific Literature | |
20. | ALA4708429 | T | Toxicity in C57/BL mouse transfected with mouse B16-F0 cells assessed as body weight loss at 10 to 20 mg/kg, ip measured after 16 days in relative to control | Mus musculus | 2 | ALA4706506 | organism-based format | Scientific Literature |