# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4730868 | F | Antibacterial activity against Porphyromonas gingivalis 381 assessed as bacterial growth inhibition at 100 uM treated for 24 hrs by WST1 assay relative to control | Porphyromonas gingivalis | 12 | ALA4725435 | organism-based format | Scientific Literature | |
2. | ALA4730870 | F | Antibacterial activity against Actinomyces naeslundii ATCC 49340 assessed as bacterial growth inhibition at 1 to 100 uM treated for 24 hrs by WST1 assay relative to control | Actinomyces naeslundii | 6 | ALA4725435 | organism-based format | Scientific Literature | |
3. | ALA4730871 | F | Antibacterial activity against Aggregatibacter actinomycetemcomitans JP2 assessed as bacterial growth inhibition at 1 to 100 uM treated for 24 hrs by WST1 assay | Aggregatibacter actinomycetemcomitans | 6 | ALA4725435 | organism-based format | Scientific Literature | |
4. | ALA4730872 | A | Cytotoxicity against hTERT-immortalized human OKF6 cells assessed as reduction in cell density at 10 uM incubated for 24 hrs by trypan blue dye based light inverted microscopic analysis | Homo sapiens | 6 | ALA4725435 | cell-based format | Scientific Literature | |
5. | ALA4730873 | F | Antibacterial activity against Streptococcus sanguinis ATCC 10556 assessed as bacterial growth inhibition at 1 to 100 uM treated for 24 hrs by WST1 assay relative to control | Streptococcus sanguinis | 6 | ALA4725435 | organism-based format | Scientific Literature | |
6. | ALA4730874 | F | Antibacterial activity against Veillonella parvula ATCC 10790 assessed as bacterial growth inhibition at 1 to 100 uM treated for 24 hrs by WST1 assay | Veillonella parvula | 6 | ALA4725435 | organism-based format | Scientific Literature | |
7. | ALA4730875 | F | Bactericidal activity against Porphyromonas gingivalis 381 assessed as growth inhibition at 100 uM treated for 24 hrs under anaerobic conditions followed by culturing in blood agar plate and measured after 5 days of incubation in an anaerobic chamber by CFU assay relative to control | Porphyromonas gingivalis | 6 | ALA4725435 | organism-based format | Scientific Literature | |
8. | ALA4730876 | F | Bactericidal activity against Porphyromonas gingivalis 381 assessed as growth inhibition at 10 uM treated for 24 hrs under anaerobic conditions followed by culturing in blood agar plate and measured after 5 days of incubation in an anaerobic chamber by CFU assay | Porphyromonas gingivalis | 6 | ALA4725435 | organism-based format | Scientific Literature | |
9. | ALA4730880 | A | Cytotoxicity against hTERT-immortalized human OKF6 cells assessed as large and flattened cell morphology at 10 uM incubated for 24 hrs by trypan blue dye based light inverted microscopic analysis | Homo sapiens | 4 | ALA4725435 | cell-based format | Scientific Literature | |
10. | ALA4730882 | A | Cytotoxicity against hTERT-immortalized human OKF6 cells assessed as cell viability at 1 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 6 | ALA4725435 | cell-based format | Scientific Literature | |
11. | ALA4730883 | A | Cytotoxicity against hTERT-immortalized human OKF6 cells assessed as cell viability at 10 uM incubated for 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 6 | ALA4725435 | cell-based format | Scientific Literature |