| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4727543 | Binding | Inhibition of ASK1 (unknown origin) | Homo sapiens | 10 | ALA4725315 | single protein format | Scientific Literature | |
| 2. | ALA4727555 | ADME | Metabolic stability in human hepatocytes assessed as hepatic extraction ratio | Homo sapiens | 1 | ALA4725315 | cell-based format | Scientific Literature | |
| 3. | ALA4727556 | ADME | Permeability across apical to basolateral side in pig LLC-PK1 cells expressing human MDR1 | Sus scrofa | 1 | ALA4725315 | cell-based format | Scientific Literature | |
| 4. | ALA4727557 | Physicochemical | Aqueous solubility of the compound in JP1 fluid at pH 1.2 | 1 | ALA4725315 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA4727558 | Physicochemical | Aqueous solubility of the compound in JP2 fluid at pH 6.5 | 1 | ALA4725315 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4727559 | ADME | Drug absorption in male Sprague-Dawley rat at 1 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4725315 | organism-based format | Scientific Literature | |
| 7. | ALA4727560 | ADME | Oral bioavailability in male Sprague-Dawley rat at 5 mg/kg | Rattus norvegicus | 1 | ALA4725315 | organism-based format | Scientific Literature | |
| 8. | ALA4727561 | Binding | Inhibition of recombinant human GST-tagged LRRK2 expressed in baculovirus expression system | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 9. | ALA4727562 | Binding | Inhibition of recombinant human full-length GST-tagged RSK3 expressed in insect cells | Homo sapiens | 1 | ALA4725315 | cell-based format | Scientific Literature | |
| 10. | ALA4727563 | Binding | Inhibition of recombinant human full-length GST-tagged PKCmu expressed in baculovirus expression system | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 11. | ALA4727564 | Binding | Inhibition of recombinant human full-length His-tagged RSK2 expressed in baculovirus expression system | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 12. | ALA4727565 | Binding | Inhibition of recombinant human full-length GST-tagged RSK4 expressed in baculovirus expression system | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 13. | ALA4727566 | Binding | Inhibition of recombinant human full-length GST-tagged PRKD2 expressed in baculovirus expression system | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 14. | ALA4727567 | Binding | Inhibition of CK1gamma1 (unknown origin) | Homo sapiens | 1 | ALA4725315 | single protein format | Scientific Literature | |
| 15. | ALA4727568 | Binding | Inhibition of CK1gamma3 (unknown origin) | Homo sapiens | 1 | ALA4725315 | single protein format | Scientific Literature | |
| 16. | ALA4727570 | Binding | Inhibition of ASK1 (unknown origin) by cell based assay | Homo sapiens | 2 | ALA4725315 | cell-based format | Scientific Literature | |
| 17. | ALA4727571 | Binding | Binding affinity to ASK1 (unknown origin) | Homo sapiens | 1 | ALA4725315 | single protein format | Scientific Literature | |
| 18. | ALA4727572 | Binding | Selectivity ratio of IC50 for inhibition of recombinant human GST-tagged LRRK2 expressed in baculovirus expression system to IC50 for inhibition of ASK1 (unknown origin) | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature | |
| 19. | ALA4727573 | Binding | Selectivity ratio of IC50 for inhibition of recombinant human full-length GST-tagged RSK3 expressed in insect cells to IC50 for inhibition of ASK1 (unknown origin) | Homo sapiens | 1 | ALA4725315 | cell-based format | Scientific Literature | |
| 20. | ALA4727574 | Binding | Selectivity ratio of IC50 for inhibition of recombinant human full-length GST-tagged PKCmu expressed in baculovirus expression system to IC50 for inhibition of ASK1 (unknown origin) | Homo sapiens | 1 | ALA4725315 | assay format | Scientific Literature |
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