| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4707172 | F | Antiproliferative activity against human PLC-PRF-5 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA4707173 | F | Antiproliferative activity against human Hep3B cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4707174 | F | Antiproliferative activity against human HuH-7 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter Glo-luminescent assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA4707176 | B | Inhibition of PI3K/AKT/mTOR signaling in human HepG2 cells assessed as AKT S473 phosphorylation level at 1 uM incubated for 4 hrs followed by stimulation with 100 ng/ml growth factor IGF1 for 15 mins by Western blot analysis (Rvb = 100 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4707178 | B | Inhibition of human PI3Kdelta incubated for 1 hr by ADP-Glo kinase assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 6. | ALA4707179 | B | Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assay | Homo sapiens | 35 | subcellular format | Scientific Literature | ||
| 7. | ALA4707180 | B | Inhibition of human full-length recombinant p110alpha/p85alpha co-expressed in baculovirus expression system using PIP2:PS lipid as substrate incubated for 1 hr in presence of ATP by ADP-Glo assay | Homo sapiens | 35 | assay format | Scientific Literature | ||
| 8. | ALA4707181 | F | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 9. | ALA4707182 | F | Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by sulforhodamine B assay/CellTiter-Glo luminescent assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 10. | ALA4707184 | B | Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 end residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4707185 | B | Inhibition of HDAC2 (unknown origin) using fluorogenic HDAC substrate 3 incubated for 30 mins by fluorescence based assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 12. | ALA4707186 | B | Inhibition of recombinant human C-terminal His-tagged HDAC3 (1 to 428 end residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA4707187 | B | Inhibition of recombinant human N-terminal GST-tagged and C-terminal His-tagged HDAC4 (627 to 1084 end residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA4707188 | B | Inhibition of HDAC5 (unknown origin) using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 15. | ALA4707189 | B | Inhibition of recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 16. | ALA4707190 | B | Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 17. | ALA4707191 | B | Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 18. | ALA4707192 | B | Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA4707193 | B | Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 20. | ALA4707194 | B | Inhibition of human full length HDAC11 expressed in baculovirus infected Sf9 cells using fluorogenic HDAC class2a as substrate measured after 30 mins by fluorescence based assay | Homo sapiens | 7 | cell-based format | Scientific Literature |
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