#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4712205	Functional	Antiproliferative activity against human HT-29 cells incubated for 3 days by WST8 assay	Homo sapiens	49	ALA4706631	cell-based format	Scientific Literature
2.	ALA4712208	Binding	Inhibition of MEK1 phosphorylation in human HT-29 cells incubated for 24 hrs by Western blot analysis	Homo sapiens	3	ALA4706631	cell-based format	Scientific Literature
3.	ALA4712209	Binding	Inhibition of MEK2 phosphorylation in human HT-29 cells incubated for 24 hrs by Western blot analysis	Homo sapiens	3	ALA4706631	cell-based format	Scientific Literature
4.	ALA4712210	Binding	Inhibition of ERK phosphorylation in human HT-29 cells incubated for 24 hrs by Western blot analysis	Homo sapiens	3	ALA4706631	cell-based format	Scientific Literature
5.	ALA4712219	Binding	Protac activity at CRBN/MEK1 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis	Homo sapiens	7	ALA4706631	cell-based format	Scientific Literature
6.	ALA4712220	Binding	Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK1 degradation at 0.3 to 3 uM incubated for 24 hrs by Western blot analysis	Homo sapiens	8	ALA4706631	cell-based format	Scientific Literature
7.	ALA4712224	Binding	Inhibition of ERK phosphorylation in human HT-29 cells assessed as time for maximum reduction in ERK phosphorylation at 0.3 uM by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
8.	ALA4712228	Binding	Protac activity at CRBN/MEK1 in human HT-29 cells assessed as time for induction of MEK1 degradation at 0.3 uM by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
9.	ALA4712229	Binding	Protac activity at CRBN/MEK2 in human HT-29 cells assessed as time for induction of MEK2 degradation at 0.3 uM by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
10.	ALA4712230	Binding	Protac activity at CRBN/MEK1 in human HT-29 cells assessed as time for maximum induction of MEK1 degradation at 0.3 uM by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
11.	ALA4712231	Binding	Protac activity at CRBN/MEK2 in human HT-29 cells assessed as time for maximum induction of MEK2 degradation at 0.3 uM by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
12.	ALA4712239	Binding	Protac activity at CRBN/MEK1 in human HT-29 cells assessed as induction of MEK1 degradation incubated for 24 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
13.	ALA4712240	Binding	Protac activity at CRBN/MEK2 in human HT-29 cells assessed as induction of MEK2 degradation incubated for 24 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
14.	ALA4712241	Binding	Protac activity at CRBN/MEK1 in human SK-MEL-28 cells assessed as induction of MEK1 degradation incubated for 24 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
15.	ALA4712242	Binding	Protac activity at CRBN/MEK2 in human SK-MEL-28 cells assessed as induction of MEK2 degradation incubated for 24 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
16.	ALA4712243	Binding	Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with MEK1/2 inhibitor PD0325901 for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
17.	ALA4712246	Binding	Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with proteasome inhibitor MG-132 for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
18.	ALA4712247	Binding	Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with neddylation inhibitor MLN4924 for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
19.	ALA4712250	Binding	Protac activity at CRBN/MEK1/2 in human HT-29 cells assessed as induction of MEK1/2 degradation pre-incubated with CRBN ligand pomalidomide for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature
20.	ALA4712251	Binding	Inhibition of MEK1/2 phosphorylation in human HT-29 cells pre-incubated with PD0325901 for 2 hrs followed by compound addition at 0.3 uM and further incubated for 8 hrs by Western blot analysis	Homo sapiens	1	ALA4706631	cell-based format	Scientific Literature