| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4731276 | Binding | Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake preincubated for 15 mins followed by [14C]uric acid addition and incubated under shaking condition for 2 hrs by scintillation counter method | Homo sapiens | 25 | ALA4725450 | tissue-based format | Scientific Literature | |
| 2. | ALA4731277 | Binding | Inhibition of URAT1 in human RPTEC assessed as inhibition of [14C]uric acid uptake at 10 uM preincubated for 15 mins followed by [14C]uric acid addition and incubated under shaking condition for 2 hrs by scintillation counter method | Homo sapiens | 17 | ALA4725450 | tissue-based format | Scientific Literature | |
| 3. | ALA4731278 | Toxicity | Hepatotoxicity in rat liver mitochondria assessed as inhibition of mitochondrial respiration by measuring mitochondrial respiratory control ratio of oxygen consumption in presence of substrate and ADP to rate after complete conversion of ADP to ATP by Clark-type oxygen electrode method | Rattus norvegicus | 15 | ALA4725450 | mitochondrion format | Scientific Literature |
The page will load shortly, Thanks for your patience!