# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4721193 | Binding | Binding affinity to human Bcl2A1 incubated for 2 hrs by FBid based competitive FP assay | Homo sapiens | 8 | ALA4715819 | single protein format | Scientific Literature | |
2. | ALA4721194 | Binding | Binding affinity to human Mcl1 incubated for 2 hrs by FBid based competitive FP assay | Homo sapiens | 8 | ALA4715819 | single protein format | Scientific Literature | |
3. | ALA4721195 | Binding | Binding affinity to human Bcl-w incubated for 2 hrs by FBid based competitive FP assay | Homo sapiens | 6 | ALA4715819 | single protein format | Scientific Literature | |
4. | ALA4721196 | Binding | Binding affinity to human Bcl-xL incubated for 2 hrs by FBid based competitive FP assay | Homo sapiens | 6 | ALA4715819 | single protein format | Scientific Literature | |
5. | ALA4721205 | Functional | Cytotoxicity in human SK-MEL-28 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA4715819 | cell-based format | Scientific Literature | |
6. | ALA4721206 | Toxicity | Toxicity in human SK-MEL-28 cells at 50 uM incubated for 30 mins by LDH release assay | Homo sapiens | 1 | ALA4715819 | cell-based format | Scientific Literature | |
7. | ALA4721207 | Binding | Inhibition of Bcl2A1-Bim interaction in human SK-MEL-28 cells at 30 uM incubated for 24 hrs by immunoprecipitation assay | Homo sapiens | 1 | ALA4715819 | cell-based format | Scientific Literature | |
8. | ALA4721208 | Binding | Inhibition of Mcl1-Bim interaction in human SK-MEL-28 cells at 30 uM incubated for 24 hrs by immunoprecipitation assay | Homo sapiens | 1 | ALA4715819 | cell-based format | Scientific Literature | |
9. | ALA4721209 | Functional | Synergistic cytotoxicity in human SK-MEL-28 cells assessed as reduction in cell viability at 1.25 to 30 uM incubated for 48 hrs in presence of etoposide by MTT assay | Homo sapiens | 1 | ALA4715819 | cell-based format | Scientific Literature |