# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4736826 | Binding | Inhibition of tracer 222 binding to GAK (unknown origin) incubated for 1 hr by Lanthascreen TR-FRET assay | Homo sapiens | 27 | ALA4732163 | single protein format | Scientific Literature | |
2. | ALA4736827 | Functional | Antiviral activity against DENV-2 New Guinea C infected in human Huh-7 cells preincubated for 1 hr followed by viral infection and measured after 48 hrs by Renilla luciferase reporter gene assay | dengue virus type 2 | 13 | ALA4732163 | organism-based format | Scientific Literature | |
3. | ALA4736828 | ADME | Cytotoxicity against DENV-2 New Guinea C infected human Huh-7 cells assessed as reduction in cell viability preincubated for 1 hr followed by viral infection and measured after 48 hrs by Alamar blue assay | Homo sapiens | 13 | ALA4732163 | cell-based format | Scientific Literature | |
4. | ALA4736829 | Binding | Inhibition of wild-type human full length CDK7 (M1 to L344 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
5. | ALA4736830 | Binding | Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
6. | ALA4736832 | Binding | Inhibition of wild-type human partial length KIT (I571 to D952 residues) expressed in bacterial expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
7. | ALA4736833 | Binding | Inhibition of wild-type human partial length MKNK2 (G63 to S388 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
8. | ALA4736834 | Binding | Inhibition of wild-type human partial length PDGFRA (V575 to D1002 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
9. | ALA4736835 | Binding | Inhibition of wild-type human partial length PDGFRB (V582 to Y1009 residues) expressed in bacterial expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature | |
10. | ALA4736836 | Binding | Inhibition of wild-type human partial length TRKA (G475 to G790 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4732163 | assay format | Scientific Literature |