# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686667 | Binding | Disaggregation of self-induced amyloid beta (1 to 42) (unknown origin) preformed fibrils at 25 uM measured after 24 hrs by thioflavin-T fluorescence assay relative to control | Homo sapiens | 25 | ALA4680246 | single protein format | Scientific Literature | |
2. | ALA4686669 | Binding | Inhibition of self-induced Amyloid beta (1 to 42 residues) (unknown origin) aggregation at 25 uM measured after 24 hrs by thioflavin T-based fluorimetric assay relative to control | Homo sapiens | 25 | ALA4680246 | single protein format | Scientific Literature | |
3. | ALA4686670 | Binding | Inhibition of recombinant human MAO-A | Homo sapiens | 25 | ALA4680246 | single protein format | Scientific Literature | |
4. | ALA4686671 | Binding | Selectivity index, ratio of IC50 for recombinant human MAO-A to IC50 for recombinant human MAO-B | Homo sapiens | 23 | ALA4680246 | assay format | Scientific Literature | |
5. | ALA4686672 | Binding | Inhibition of recombinant human MAO-B | Homo sapiens | 25 | ALA4680246 | single protein format | Scientific Literature | |
6. | ALA4686679 | Binding | Selectivity index, ratio of IC50 for human erythrocytes Ache to IC50 for human serum BuChe | Homo sapiens | 22 | ALA4680246 | assay format | Scientific Literature | |
7. | ALA4686680 | Binding | Inhibition of human serum BuChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's method | Homo sapiens | 23 | ALA4680246 | single protein format | Scientific Literature | |
8. | ALA4686681 | ADME | Inhibition of human erythrocytes AChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's method | Homo sapiens | 23 | ALA4680246 | assay format | Scientific Literature | |
9. | ALA4686682 | Binding | Inhibition of equine serum BuChE using BTC as substrate after 15 mins by Ellman's method | Equus caballus | 23 | ALA4680246 | single protein format | Scientific Literature | |
10. | ALA4686684 | ADME | Inhibition of Electrophorus electricus AChE using acetylcholine iodide as substrate incubated for 15 mins by Ellman's method | Electrophorus electricus | 23 | ALA4680246 | single protein format | Scientific Literature |