# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4679738 | Binding | Binding affinity to BTN3A1 in human K562 cells assessed as induction of Vgamma9/Vdelta2 T cell-mediated interferon gamma release preincubated for 4 hrs followed by compound washout and subsequent Vgamma9Vdelta2 T cell addition measured after 20 hrs by ELISA | Homo sapiens | 2 | ALA4673393 | cell-based format | Scientific Literature | |
2. | ALA4679740 | Binding | Binding affinity to BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of Vgamma9Vdelta2 T cells proliferation incubated for 3 days by gamma delta TCR/PE-CD3+ antibody staining based FACS analysis | Homo sapiens | 12 | ALA4673393 | tissue-based format | Scientific Literature | |
3. | ALA4679741 | Binding | Binding affinity to BTN3A1 in human PBMC-derived Vgamma9/Vdelta2 T cells assessed as induction of Vgamma9Vdelta2 T cells proliferation incubated for 3 days by gamma delta TCR/PE-CD3+ antibody staining based FACS analysis relative to HMBP analog | Homo sapiens | 7 | ALA4673393 | tissue-based format | Scientific Literature |