| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4708980 | B | Inhibition of human DNA topoisomerase 2alpha assessed as suppression of decatenation using catenated kinetoplast DNA as substrate measured after 30 mins by SYBR safe DNA staining based staining-based agarose gel electrophoresis method | Homo sapiens | 4 | ALA4706523 | single protein format | Scientific Literature | |
| 2. | ALA4708981 | B | Potency index, ratio of etoposide IC50 to test compound IC50 for inhibition of human DNA topoisomerase 2alpha | Homo sapiens | 1 | ALA4706523 | single protein format | Scientific Literature | |
| 3. | ALA4708982 | B | Poison activity at human DNA topoisomerase 2 alpha assessed as stabilization of cleavage complex using PBR322 as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 1 | ALA4706523 | single protein format | Scientific Literature | |
| 4. | ALA4708984 | F | Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 5. | ALA4708985 | F | Antiproliferative activity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 2 | ALA4706523 | cell-based format | Scientific Literature | |
| 6. | ALA4708986 | F | Antiproliferative activity against human CEM/C2 cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 7. | ALA4708987 | F | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 8. | ALA4708988 | F | Antiproliferative activity against human HT29 cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 9. | ALA4708989 | F | Antiproliferative activity against human DLD-1 cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 10. | ALA4708990 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by eosin exclusion dye based light microscopic method | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 11. | ALA4708991 | B | Selectivity ratio of IC50 for antiproliferative activity against human CCRF-CEM cells to IC50 for antiproliferative activity against human Jurkat cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 12. | ALA4708992 | B | Selectivity ratio of IC50 for antiproliferative activity against human CCRF-CEM cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 13. | ALA4708993 | B | Selectivity ratio of IC50 for antiproliferative activity against human CEM/C2 cells to IC50 for antiproliferative activity against human Jurkat cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 14. | ALA4708994 | B | Selectivity ratio of IC50 for antiproliferative activity against human CEM/C2 cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 15. | ALA4708995 | B | Selectivity ratio of IC50 for antiproliferative activity against human HL-60 cells to IC50 for antiproliferative activity against human Jurkat cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 16. | ALA4708996 | B | Selectivity ratio of IC50 for antiproliferative activity against human HL-60 cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 17. | ALA4708997 | B | Selectivity ratio of IC50 for antiproliferative activity against human HT-29 cells to IC50 for antiproliferative activity against human Jurkat cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 18. | ALA4708998 | B | Selectivity ratio of IC50 for antiproliferative activity against human HT-29 cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 19. | ALA4708999 | B | Selectivity ratio of IC50 for antiproliferative activity against human DLD-1 cells to IC50 for antiproliferative activity against human Jurkat cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature | |
| 20. | ALA4709000 | B | Selectivity ratio of IC50 for antiproliferative activity against human DLD-1 cells to IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 1 | ALA4706523 | cell-based format | Scientific Literature |
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