| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4738224 | F | Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 2. | ALA4738225 | F | Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay relative to control | Homo sapiens | 3 | ALA4732214 | cell-based format | Scientific Literature | |
| 3. | ALA4738226 | F | Allosteric antagonist activity at eFYP-tagged human NPY4R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced inositol phosphate accumulation by IP-one assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 4. | ALA4738238 | B | Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport by electrophysiology | Mus musculus | 1 | ALA4732214 | single protein format | Scientific Literature | |
| 5. | ALA4738239 | B | Allosteric antagonist activity at NPY5R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 30 uM by electrophysiology | Mus musculus | 1 | ALA4732214 | single protein format | Scientific Literature | |
| 6. | ALA4738240 | B | Allosteric antagonist activity at NPY1R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 0.3 to 30 uM by electrophysiology | Mus musculus | 2 | ALA4732214 | single protein format | Scientific Literature | |
| 7. | ALA4738241 | B | Allosteric antagonist activity at NPY2R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 0.3 to 30 uM by electrophysiology | Mus musculus | 2 | ALA4732214 | single protein format | Scientific Literature | |
| 8. | ALA4738242 | B | Allosteric antagonist activity at NPY1R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 30 uM by electrophysiology | Mus musculus | 2 | ALA4732214 | single protein format | Scientific Literature | |
| 9. | ALA4738243 | B | Allosteric antagonist activity at NPY2R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 30 uM by electrophysiology | Mus musculus | 2 | ALA4732214 | single protein format | Scientific Literature | |
| 10. | ALA4738247 | B | Allosteric antagonist activity at human NPY4R Y1.39 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 11. | ALA4738248 | B | Allosteric antagonist activity at human NPY4R Q2.58 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 12. | ALA4738249 | B | Allosteric antagonist activity at human NPY4R T2.61 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 13. | ALA4738250 | B | Allosteric antagonist activity at human NPY4R Y2.64 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 14. | ALA4738251 | B | Allosteric antagonist activity at human NPY4R W2.70 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 15. | ALA4738252 | B | Allosteric antagonist activity at human NPY4R S3.28 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 16. | ALA4738253 | B | Allosteric antagonist activity at human NPY4R A3.29 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 17. | ALA4738254 | B | Allosteric antagonist activity at human NPY4R Q3.32 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 18. | ALA4738255 | B | Allosteric antagonist activity at human NPY4R F4.60 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 19. | ALA4738256 | B | Allosteric antagonist activity at human NPY4R F7.35 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature | |
| 20. | ALA4738257 | B | Allosteric antagonist activity at human NPY4R L7.36 position mutant expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of PP-induced Ca2+ flux by Fluo-2 AM dye based fluorescent assay | Homo sapiens | 1 | ALA4732214 | cell-based format | Scientific Literature |
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