| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4684781 | F | Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth at 8 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 2. | ALA4684782 | F | Antiproliferative activity against human H460 cells assessed as inhibition of cell growth at 8 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 3. | ALA4684783 | B | Inhibition of human recombinant HDAC1 at 10 uM preincubated for 10 mins followed by addition of substrate fluor De Lys SIRT1 deacetylase measured after 30 mins by fluorescent plate reader analysis relative to control | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 4. | ALA4684784 | B | Inhibition of recombinant human full length CDK2/cyclin A2 at 10 uM incubated for 10 mins by ADP-Glo reagent assay relative to control | Homo sapiens | 36 | protein complex format | Scientific Literature | ||
| 5. | ALA4684785 | F | Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 6. | ALA4684786 | F | Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 7. | ALA4684787 | F | Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 8. | ALA4684788 | F | Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 9. | ALA4684789 | F | Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 10. | ALA4684790 | A | Cytotoxicity against mouse NIH/3T3 cells incubated for 72 hrs by CCK-8 assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4684791 | B | Inhibition of human recombinant HDAC1 preincubated for 10 mins followed by addition of substrate fluor De Lys SIRT1 deacetylase measured after 30 mins by fluorescent plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA4684792 | B | Inhibition of human recombinant HDAC2 preincubated for 10 mins followed by addition of substrate fluor De Lys green measured after 30 mins by fluorescent plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4684793 | B | Inhibition of human recombinant HDAC3/NCOR1 complex preincubated for 10 mins followed by addition of substrate fluor De Lys SIRT1 deacetylase measured after 30 mins by fluorescent plate reader analysis | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 14. | ALA4684794 | B | Inhibition of human recombinant HDAC6 preincubated for 10 mins followed by addition of substrate fluor De Lys SIRT1 deacetylase measured after 30 mins by fluorescent plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4684795 | B | Inhibition of human recombinant HDAC8 preincubated for 10 mins followed by substrate addition measured after 30 mins by fluorescent plate reader analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA4684796 | B | Inhibition of recombinant human full length CDK1/cyclin A2 expressed in Sf9 cells incubated for 10 mins by ADP-Glo reagent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4684797 | B | Inhibition of recombinant human full length CDK2/cyclin A2 incubated for 10 mins by ADP-Glo reagent assay | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 18. | ALA4684798 | B | Inhibition of recombinant human full length CDK4/cyclin D1 expressed in Sf9 cells incubated for 10 mins by ADP-Glo reagent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4684799 | B | Inhibition of recombinant human full length CDK6/cyclin D3 incubated for 10 mins by ADP-Glo reagent assay | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 20. | ALA4684800 | B | Inhibition of recombinant human full length CDK7/cyclin H1 expressed in Sf9 cells incubated for 10 mins by ADP-Glo reagent assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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