# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4669861 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-8 mRNA expression at 1 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA4669862 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-6 mRNA expression at 1 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA4669863 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-6 mRNA expression at 500 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4669864 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-1beta mRNA expression at 500 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4669865 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-8 mRNA expression at 500 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4669866 | B | Binding affinity to N-terminal domain of human galectin-8 (8-154 residues) by ITC assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
7. | ALA4669867 | B | Potency index, ratio of Kd for lactose to Kd for test compound for binding affinity to N-terminal domain of human galectin-8 (8-154 residues) by ITC assay | Homo sapiens | 1 | single protein format | Scientific Literature |