# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4715191 | F | Antagonist activity in CXCR2 (unknown origin) expressed in human HEK293 cells co-expressing Galpha16 assessed as reduction in calcium immobilization pretreated with Fluo-4AM for 45 mins followed by compound addition and measured after 10 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA4715192 | F | Antagonist activity in CXCR1 (unknown origin) expressed in human HEK293 cells co-expressing Galpha16 assessed as reduction in calcium immobilization pretreated with Fluo-4AM for 45 mins followed by compound addition and measured after 10 mins by Fluo-4AM dye based fluorescence assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA4715193 | B | Selectivity index, ratio of IC50 for CXCR1 (unknown origin) expressed in human HEK293 cells to IC50 for CXCR2 (unknown origin) expressed in human HEK293 cells | Homo sapiens | 23 | cell-based format | Scientific Literature |