# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4711229 | F | Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA4711230 | F | Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA4711231 | F | Antiproliferative activity against human RS4-11 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
4. | ALA4711232 | F | Antiproliferative activity against human CCRF-CEM cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
5. | ALA4711237 | B | Binding affinity to human CKalpha1 assessed as dissociation constant by spectroflurometry | Homo sapiens | 12 | single protein format | Scientific Literature | ||
6. | ALA4711238 | B | Binding affinity to human CKbeta assessed as dissociation constant by spectroflurometry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA4711239 | B | Selectivity index, ratio of Kd for human CKbeta to Kd for human CKalpha1 | Homo sapiens | 4 | assay format | Scientific Literature | ||
8. | ALA4711240 | B | Inhibition of human CKalpha1 assessed as reduction in 14C incorporation from [methyl-14C]choline to phosphatidylcholine at 10 uM using [methyl-14C]choline as substrate preincubated for 5 mins in presence of ATP and MgCl2 followed by substrate addition and measured after 10 mins by liquid scintillation counting method relative to control | Homo sapiens | 14 | single protein format | Scientific Literature | ||
9. | ALA4711241 | B | Inhibition of human CKalpha1 assessed as reduction in 14C incorporation from [methyl-14C]choline to phosphatidylcholine at 30 uM using [methyl-14C]choline as substrate preincubated for 5 mins in presence of ATP and MgCl2 followed by substrate addition and measured after 10 mins by liquid scintillation counting method relative to control | Homo sapiens | 17 | single protein format | Scientific Literature | ||
10. | ALA4711243 | B | Inhibition of human CKalpha1 assessed as reduction in 14C incorporation from [methyl-14C]choline to phosphatidylcholine using [methyl-14C]choline as substrate preincubated for 5 mins in presence of ATP and MgCl2 followed by substrate addition and measured after 10 mins by liquid scintillation counting method relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA4711244 | F | Inhibition of [methyl-14C]choline uptake in human HT-29 cells at 10 uM incubated for 10 mins followed by removal of medium containing compound and subsequent addition of [methyl-14C]choline measured after 5 mins relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
12. | ALA4711245 | F | Inhibition of [methyl-14C]choline uptake in human HT-29 cells at 30 uM incubated for 10 mins followed by removal of medium containing compound and subsequent addition of [methyl-14C]choline measured after 5 mins relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
13. | ALA4711246 | F | Inhibition of [methyl-14C]choline uptake in human HepG2 cells at 10 uM incubated for 10 mins followed by removal of medium containing compound and subsequent addition of [methyl-14C]choline measured after 5 mins relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
14. | ALA4711247 | F | Inhibition of [methyl-14C]choline uptake in human HepG2 cells at 30 uM incubated for 10 mins followed by removal of medium containing compound and subsequent addition of [methyl-14C]choline measured after 5 mins relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature |