| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4672001 | A | Metabolic stability in cryopreserved human hepatocytes assessed as half-life at 1 uM incubated for 4 hrs | Homo sapiens | 23 | ALA4665847 | cell-based format | Scientific Literature | |
| 2. | ALA4672003 | A | Metabolic stability in human liver cytosol assessed as AOX1 mediated drug metabolism by measuring half-life at 1 uM incubated up to 90 mins by LC-MS/MS analysis | Homo sapiens | 2 | ALA4665847 | subcellular format | Scientific Literature | |
| 3. | ALA4672011 | A | Metabolic stability in human liver cytosol assessed as AOX1 mediated drug metabolism by measuring amide hydrolysis at 1 uM incubated up to 90 mins in presence of hydralazine by LC-MS/MS analysis | Homo sapiens | 2 | ALA4665847 | subcellular format | Scientific Literature | |
| 4. | ALA4672012 | A | Metabolic stability in human liver cytosol assessed as AOX1 mediated drug metabolism by measuring hydroxylation at 1 uM incubated up to 90 mins in absence of hydralazine by LC-MS/MS analysis | Homo sapiens | 2 | ALA4665847 | subcellular format | Scientific Literature | |
| 5. | ALA4714846 | F | Antiproliferative activity against human 22Rv1 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by automated cell counting analysis relative to control | Homo sapiens | 11 | ALA4706736 | cell-based format | Scientific Literature | |
| 6. | ALA5141007 | B | Protac activity at VHL (unknown origin)/Androgen receptor (unknown origin) assessed as full-length Androgen receptor degradation measured by immunoblotting method | Homo sapiens | 1 | ALA5137058 | protein format | Scientific Literature | |
| 7. | ALA5141008 | B | Protac activity at VHL (unknown origin)/Androgen receptor splice variant7 (unknown origin) assessed as Androgen receptor degradation measured by immunoblotting method | Homo sapiens | 1 | ALA5137058 | assay format | Scientific Literature | |
| 8. | ALA5239283 | B | PROTAC activity at VHL/AR-V7 in human 22Rv1 cells assessed as induction of AR-V7 degradation incubated for 24 hrs by immunoblot assay | Homo sapiens | 1 | ALA5236610 | cell-based format | Scientific Literature | |
| 9. | ALA5239284 | B | PROTAC activity at VHL/full length AR in human 22Rv1 cells assessed as induction of AR degradation incubated for 24 hrs by immunoblot assay | Homo sapiens | 1 | ALA5236610 | cell-based format | Scientific Literature |
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