# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4689515 | Functional | Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 3 days by CellTiter-Glo assay | Homo sapiens | 10 | ALA4680361 | cell-based format | Scientific Literature | |
2. | ALA4689516 | Binding | Protac activity at CRBN/JAK2 V617 mutant in human HEL cells assessed as decrease in JAK2 V617 mutant protein level at < 60 nM measured after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4680361 | cell-based format | Scientific Literature | |
3. | ALA4689517 | Binding | Protac activity at CRBN/JAK1 in human RS4-11 cells assessed as degradation of JAK1 measured after 24 hrs by immunoblotting analysis | Homo sapiens | 2 | ALA4680361 | cell-based format | Scientific Literature | |
4. | ALA4689518 | ADME | Cytotoxicity against human IMR-90 cells assessed as effect on cell viability at 10^-10 to 10^-5 M measured after 3 days by CellTiter-Glo assay | Homo sapiens | 2 | ALA4680361 | cell-based format | Scientific Literature | |
5. | ALA4689519 | ADME | Cytotoxicity against human HaCaT cells assessed as effect on cell viability at 10^-10 to 10^-5 M measured after 3 days by CellTiter-Glo assay | Homo sapiens | 2 | ALA4680361 | cell-based format | Scientific Literature |