| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4739797 | B | Inhibition of biotinylated-THZ1 binding to CDK7 in human Jurkat cells assessed as reduction in cyclin H pull down at 1 uM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pull-down assay | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
| 2. | ALA4739798 | B | Inhibition of biotinylated-THZ1 binding to CDK12 in human Jurkat cells assessed as reduction in cyclin K pull down at 1 uM preincubated for 6 hrs followed by biotinylated-THZ1 addition by Western blotting based pull-down assay | Homo sapiens | 6 | cell-based format | Patent Bioactivity Data | ||
| 3. | ALA4739800 | B | Inhibition of CDK2/cyclin A (unknown origin) | Homo sapiens | 13 | protein complex format | Patent Bioactivity Data | ||
| 4. | ALA4739801 | B | Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) | Homo sapiens | 13 | protein complex format | Patent Bioactivity Data | ||
| 5. | ALA4739802 | B | Inhibition of CDK9/cyclin T1 (unknown origin) | Homo sapiens | 13 | protein complex format | Patent Bioactivity Data | ||
| 6. | ALA4828798 | B | Inhibition of CDK2/Cyclin A (unknown origin) | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 7. | ALA4828799 | B | Inhibition of CDK7/Cyclin H (unknown origin) | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 8. | ALA4828800 | B | Inhibition of CDK9/Cyclin T1 (unknown origin) | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 9. | ALA4828801 | B | Inhibition of human recombinant CDK12/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzyme for 5 mins followed by substrate addition for 15 mins in presence of [gamma 32P-ATP] by radioactive kinase assay | Homo sapiens | 20 | protein complex format | Scientific Literature | ||
| 10. | ALA4828802 | B | Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzyme for 5 mins followed by substrate addition for 15 mins in presence of [gamma 32P-ATP] by radioactive kinase assay | Homo sapiens | 20 | protein complex format | Scientific Literature |
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