# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4672455 | B | Potency index, ratio of crizotinib IC50 to test compound IC50 for inhibition of ROS1 (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4672456 | B | Potency index, ratio of ceritinib IC50 to test compound IC50 for inhibition of ALK (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA4672457 | B | Potency index, ratio of ceritinib IC50 to test compound IC50 for inhibition of ALK G1202R mutant (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA4672458 | B | Potency index, ratio of ceritinib IC50 to test compound IC50 for inhibition of ROS1 (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA4672459 | B | Potency index, ratio of ceritinib IC50 to test compound IC50 for inhibition of ALK L1196M mutant (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA4672460 | B | Potency index, ratio of crizotinib IC50 to test compound IC50 for inhibition of ALK (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA4672461 | B | Inhibition of ROS1 (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
8. | ALA4672462 | B | Inhibition of c-Met (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
9. | ALA4672463 | B | Inhibition of ALK G1202R mutant (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
10. | ALA4672464 | B | Inhibition of ALK L1196M mutant (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
11. | ALA4672465 | F | Cytotoxicity against human KARPAS299 cells harboring NMP-ALK incubated for 72 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
12. | ALA4672466 | F | Cytotoxicity against human HCC78 cells harboring SLC34A2-ROS1 incubated for 72 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
13. | ALA4672467 | A | Cytotoxicity against EGFR-positive human A549 cells incubated for 72 hrs by MTT assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
14. | ALA4672469 | B | Inhibition of ALK (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assay | Homo sapiens | 6 | single protein format | Scientific Literature |