#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4682948	B	Inhibition of IDO1/TDO in IFNgamma-stimulated human A172 cells assessed as reduction in kynurenine formation at 100 uM using L-tryptophan as substrate incubated for 48 hrs by microplate reader analysis relative to control	Homo sapiens	1	ALA4680135	tissue-based format	Scientific Literature
2.	ALA4682949	B	Inhibition of recombinant human IDO1 assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplate reader assay	Homo sapiens	76	ALA4680135	single protein format	Scientific Literature
3.	ALA4682950	B	Inhibition of recombinant human TDO assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplate reader assay	Homo sapiens	75	ALA4680135	single protein format	Scientific Literature
4.	ALA4682951	B	Inhibition of IDO1/TDO in IFNgamma-stimulated human A172 cells assessed as reduction in kynurenine formation at 50 uM using L-tryptophan as substrate incubated for 48 hrs by microplate reader analysis relative to control	Homo sapiens	1	ALA4680135	tissue-based format	Scientific Literature
5.	ALA4682952	B	Reversal of IDO1/TDO-mediated suppression of mouse T-lymphocyte proliferation assessed as increase in mytomycin C treated LLC cells stimulated T-cells proliferation at 10 uM incubated for 3 days by Cell Titer Glo luminescent cell viability assay	Mus musculus	1	ALA4680135	cell-based format	Scientific Literature
6.	ALA4682953	F	Antitumor activity against mouse B16F10 cells xenografted in C57BL6 mouse assessed as tumor growth inhibition at 50 mg/kg, po administered for 19 consecutive days relative to control	Mus musculus	1	ALA4680135	organism-based format	Scientific Literature
7.	ALA4682954	F	Antitumor activity against mouse B16F10 cells xenografted in C57BL/6 mouse assessed as tumor growth inhibition at 100 mg/kg, po administered for 19 consecutive days relative to control	Mus musculus	1	ALA4680135	organism-based format	Scientific Literature
8.	ALA4682955	T	Toxicity in C57BL/6 mouse xenografted with mouse B16F10 cells assessed as body weight loss at 50 to 100 mg/kg, po administered for 19 consecutive days	Mus musculus	1	ALA4680135	organism-based format	Scientific Literature
9.	ALA5216253	B	Inhibition of IDO1 (unknown origin)	Homo sapiens	12	ALA5214925	single protein format	Scientific Literature
10.	ALA5216254	B	Inhibition of TDO (unknown origin)	Homo sapiens	7	ALA5214925	single protein format	Scientific Literature
11.	ALA5216258	F	Antiproliferative activity against melanoma cells (unknown origin) subcutaneously xenografted in mouse model assessed as inhibition of cell growth rate at 50 mg/kg relative to control	Not specified	1	ALA5214925	organism-based format	Scientific Literature
12.	ALA5216259	F	Antiproliferative activity against melanoma cells (unknown origin) subcutaneously xenografted in mouse model assessed as inhibition of cell growth rate at 100 mg/kg relative to control	Not specified	1	ALA5214925	organism-based format	Scientific Literature