# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4713462 | T | Toxicity in lean Sprague-Dawley rat assessed as induction of emesis at 0.3 to 60 nmol/kg dosed daily for 2 days by kaolin consumption assay | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
2. | ALA4713464 | F | Agonist activity at human GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA4713465 | F | Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
4. | ALA4713466 | F | Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
5. | ALA4713467 | F | Agonist activity at rat glucagon receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assay | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
6. | ALA4713470 | F | Agonist activity at rat GLP-1R expressed in HEK293 cells assessed as stimulation of cAMP accumulation by FRET assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4713471 | B | Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
8. | ALA4713474 | A | Half life in Sprague-Dawley rat liver microsomes at 30 uM in presence of NADPH by HPLC analysis | Rattus norvegicus | 3 | microsome format | Scientific Literature | ||
9. | ALA4713475 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes at 30 uM in presence of NADPH by HPLC analysis | Rattus norvegicus | 3 | microsome format | Scientific Literature |