| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4673815 | B | Binding affinity to MTH1 in human K562 cells assessed as thermal stabilization preincubated for 30 mins followed by heating at 52 degree C for 3 mins by CETSA-based Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA4673818 | A | Efflux ratio of permeability in human Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4673820 | A | Apparent permeability of compound in human Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4673824 | P | Aqueous solubility of compound at pH 7.4 | 13 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4673826 | A | Plasma protein binding in human assessed as fraction unbound | Homo sapiens | 21 | cell-free format | Scientific Literature | ||
| 6. | ALA4673827 | A | Intrinsic clearance in human liver microsome | Homo sapiens | 21 | microsome format | Scientific Literature | ||
| 7. | ALA4673828 | P | Lipophilicity, log D of compound at pH 7.4 | 23 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA4673830 | B | Inhibition of MTH1 (unknown origin) using 8-oxo-dGTP as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by PPiLight detection reagent based luminescence assay | Homo sapiens | 26 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!