| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4700370 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA4700371 | F | Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA4700372 | F | Antiproliferative activity against human MCF-7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 4. | ALA4700373 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 5. | ALA4700375 | A | Cytotoxicity against human peripheral blood mononuclear cells assessed as reduction in cell survival at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA4700376 | A | Cytotoxicity against human HBL-100 cells assessed as reduction in cell survival at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4700377 | B | Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophotometric method | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 8. | ALA4700378 | F | Induction of reactive oxygen species generation in human MDA-MB-231 cells assessed as increase in intracellular ROS level at sub-IC50 concentration incubated for 48 hrs by H2DCFDA staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4700379 | F | Induction of mitochondrial membrane potential depolarization in human MDA-MB-231 cells assessed as increase in red fluorescence to green fluorescence ratio at sub-IC50 concentration incubated for 48 hrs by JC1 staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4700380 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of cells at G0 phase at sub-IC50 concentration measured after 48 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 2.54%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4700381 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of cells at G1 phase at sub-IC50 concentration measured after 48 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 56.22%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4700382 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of cells at S phase at sub-IC50 concentration measured after 48 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 8.97%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4700383 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of cells at G2/M phase at sub-IC50 concentration measured after 48 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 8.69%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4700384 | B | Inhibition of CDK2/Cyclin A (unknown origin) using Ser/Thr 12 peptide as substrate incubated for 1 hr | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 15. | ALA4700385 | B | Inhibition of CDK4/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hr | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA4700386 | B | Inhibition of CDK6/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hr | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 17. | ALA4700387 | A | Cytotoxicity against human HBL-100 cells assessed as disruption of cell morphology at 10 uM | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4700388 | B | Inhibition of CDK4/Cyclin D3 (unknown origin) using Rb protein as substrate incubated for 1 hr | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 19. | ALA4700389 | F | Antiproliferative activity against human H1299 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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