# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4669204 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of IL2-induced STAT5 phosphorylation at 150 uM preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature | |
2. | ALA4669205 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of GM-CSF-induced STAT5 phosphorylation at 150 uM preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature | |
3. | ALA4669206 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of IFNalpha-induced STAT1 phosphorylation at 150 uM preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature | |
4. | ALA4669207 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of IL2-induced STAT5 phosphorylation preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature | |
5. | ALA4669208 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of GM-CSF-induced STAT5 phosphorylation preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature | |
6. | ALA4669209 | Binding | Inhibition of JAK in human PBMC assessed as inhibition of IFNalpha-induced STAT1 phosphorylation preincubated for 30 mins followed by addition IL2 stimulation and measured after 30 mins by ELISA | Homo sapiens | 1 | ALA4665715 | tissue-based format | Scientific Literature |