| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4719886 | B | Agonist activity at human S1P3 expressed in EDG3-Ga15-bla HEK293T cells incubated for 45 mins by scintillation counting based [35S]GTP-gamma-S binding assay relative to control | Homo sapiens | 4 | cell membrane format | Scientific Literature | ||
| 2. | ALA4719889 | F | Induction of lymphopenia in Balb/c mouse assessed as reduction of circulating lymphocytes at 1 mg/kg, po measured after 4 hrs relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA4719890 | F | Induction of lymphopenia in Balb/c mouse assessed as reduction of circulating lymphocytes at 1 mg/kg, po measured after 24 hrs relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA4719891 | F | Induction of lymphopenia in Balb/c mouse assessed as reduction of circulating lymphocytes at 10 mg/kg, po measured after 4 hrs relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA4719892 | F | Induction of lymphopenia in Balb/c mouse assessed as reduction of circulating lymphocytes at 10 mg/kg, po measured after 24 hrs relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA4719894 | B | Inhibition of human ERG expressed in HEK293 cells assessed as inhibition of peak tail current at 0.3 uM by patch clamp analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4719895 | B | Inhibition of sodium channel (unknown origin) assessed as reduction in Na+ flux | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 8. | ALA4719896 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA4719897 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA4719898 | A | Inhibition of CYP2C8 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 11. | ALA4719899 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA4719900 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA4719901 | A | Half life in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 14. | ALA4719902 | A | Half life in rat liver microsomes | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 15. | ALA4719903 | A | Half life in mouse liver microsomes | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 16. | ALA4719904 | A | Half life in monkey liver microsomes | Macaca mulatta | 2 | microsome format | Scientific Literature | ||
| 17. | ALA4719905 | A | Unbound fraction in human plasma | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 18. | ALA4719906 | A | Unbound fraction in rat plasma | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
| 19. | ALA4719907 | A | Unbound fraction in mouse plasma | Mus musculus | 2 | cell-free format | Scientific Literature | ||
| 20. | ALA4719908 | A | Unbound fraction in cynomolgus monkey plasma | Macaca fascicularis | 2 | cell-free format | Scientific Literature |
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