| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4739198 | Binding | Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins followed by substrate and ATP addition at Km concentration measured after 120 mins by RapidFire LC-MS analysis | Homo sapiens | 23 | ALA4732252 | single protein format | Scientific Literature | |
| 2. | ALA4739199 | Binding | Inhibition of GST-tagged Tyro3 (unknown origin) (453 to 890 residues) using Axltide (KKSRGDYMTMQIG-acid) peptide as substrate preincubated for 30 mins followed by substrate and ATP addition at Km concentration measured after 180 mins by RapidFire LC-MS analysis | Homo sapiens | 23 | ALA4732252 | single protein format | Scientific Literature | |
| 3. | ALA4739201 | ADME | Intrinsic clearance in rat hepatocytes assessed per 10^6 cells | Rattus norvegicus | 23 | ALA4732252 | cell-based format | Scientific Literature | |
| 4. | ALA4739202 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 23 | ALA4732252 | microsome format | Scientific Literature | |
| 5. | ALA4739203 | Physicochemical | Distribution coefficient, logD of compound at pH 7.4 | 23 | ALA4732252 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4739204 | Physicochemical | Aqueous solubility of the compound | 23 | ALA4732252 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4739205 | Binding | Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins followed by substrate and ATP addition at Km concentration measured after 40 mins by ADP-Glo Reagent based method | Homo sapiens | 3 | ALA4732252 | single protein format | Scientific Literature | |
| 8. | ALA4739206 | Binding | Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincubated for 30 mins followed by substrate addition in presence of ATP and measured for 90 mins by ADP-Glo Reagent based method | Homo sapiens | 3 | ALA4732252 | single protein format | Scientific Literature |
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