# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4729810 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrate preincubated for 1 hr followed by substrate addition | Homo sapiens | 108 | assay format | Scientific Literature | ||
2. | ALA4729834 | A | Binding affinity to fetal bovine serum albumin at 20 uM measured after overnight incubation in presence of cell free DMEM medium by gel based assay | Bos taurus | 2 | cell-free format | Scientific Literature | ||
3. | ALA4729838 | B | Binding affinity to PDIA1 in human U-87 MG cells at 5 uM measured after 24 hrs in presence of DTT by coomassie staining GFP channel based Western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4729839 | B | Binding affinity to PDIA1 in human U-87 MG cell lysates at 5 uM measured after 24 hrs by PAGE analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
5. | ALA4729840 | A | Binding affinity to BSA at 100 uM measured after overnight incubation by coomassie staining GFP channel based Western blot assay | Bos taurus | 1 | cell-free format | Scientific Literature | ||
6. | ALA4729844 | B | Binding affinity to recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 20 uM measured after 24 hrs in presence of BSA by SDS PAGE analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA4729845 | A | Drug uptake in human A 172 cell cytoplasm at 10 uM measured after 24 hrs by PDI antibody/DAPI staining based confocal microscopic analysis | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
8. | ALA4729846 | A | Drug uptake in human A 172 cell endoplasmic reticulum at 10 uM measured after 24 hrs by PDI antibody/DAPI staining based confocal microscopic analysis | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
9. | ALA4729847 | A | Drug uptake in human A 172 cell nucleus at 10 uM measured after 24 hrs by PDI antibody/DAPI staining based confocal microscopic analysis | Homo sapiens | 2 | subcellular format | Scientific Literature |