# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4712494 | Binding | Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract preincubated for 30 mins followed by hSIE probe addition by EMSA analysis | Mus musculus | 37 | ALA4706639 | subcellular format | Scientific Literature | |
2. | ALA4712495 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 47 | ALA4706639 | cell-based format | Scientific Literature | |
3. | ALA4712496 | Functional | Antiproliferative activity against human MDA-MB-468 cells harbouring STAT3 assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 42 | ALA4706639 | cell-based format | Scientific Literature | |
4. | ALA4712497 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 44 | ALA4706639 | cell-based format | Scientific Literature | |
5. | ALA4712498 | ADME | Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by CyQuant assay | Homo sapiens | 42 | ALA4706639 | cell-based format | Scientific Literature | |
6. | ALA4712524 | Functional | Anticlonogenic activity against human MDA-MB-231 cells assessed as inhibition of colony formation at 0.5 to 1 uM incubated for 4 hrs by crystal violet staining based assay | Homo sapiens | 3 | ALA4706639 | cell-based format | Scientific Literature |