# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685439 | B | Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Detection kit method | Homo sapiens | 41 | ALA4680207 | cell-based format | Scientific Literature | |
2. | ALA4685440 | A | Agonist activity at recombinant human AC1 expressed in HEK293 cells assessed as increase in cAMP level at 50 uM measured after 30 mins by LANCE Ultra cAMP Detection kit method | Homo sapiens | 1 | ALA4680207 | cell-based format | Scientific Literature | |
3. | ALA4685441 | A | Agonist activity at recombinant human AC5 expressed in HEK293 cells assessed as increase in cAMP level at 50 uM measured after 30 mins by LANCE Ultra cAMP Detection kit method | Homo sapiens | 1 | ALA4680207 | cell-based format | Scientific Literature | |
4. | ALA4685442 | A | Agonist activity at recombinant human AC8 expressed in HEK293 cells assessed as increase in cAMP level at 50 uM measured after 30 mins by LANCE Ultra cAMP Detection kit method | Homo sapiens | 3 | ALA4680207 | cell-based format | Scientific Literature | |
5. | ALA4685443 | B | Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level by measuring cAMP level at 50 uM measured after 30 mins by LANCE Ultra cAMP Detection kit method relative to control | Homo sapiens | 59 | ALA4680207 | cell-based format | Scientific Literature | |
6. | ALA4685444 | B | Potency index, ratio of forskolin EC50 to test compound EC50 for agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level | Homo sapiens | 1 | ALA4680207 | cell-based format | Scientific Literature | |
7. | ALA4685445 | B | Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as reduction in IL6 level by measuring IL6 level at 50 uM measured after 24 hrs by ELISA relative to control | Homo sapiens | 2 | ALA4680207 | cell-based format | Scientific Literature |