# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4705014 | B | Competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as inhibition constant using PEA as substrate in presence of 100 uM AdoMet as co-substrate by Sigma-plot analysis | Homo sapiens | 21 | assay format | Scientific Literature | ||
2. | ALA4705015 | B | Non-competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as slope inhibition constant in presence of 5 uM PEA as substrate and AdoMet as co-substrate by Sigma-plot analysis | Homo sapiens | 21 | assay format | Scientific Literature | ||
3. | ALA4705016 | B | Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assay | Rattus norvegicus | 17 | single protein format | Scientific Literature | ||
4. | ALA4705017 | B | Selectivity index, ratio of Ki for alpha2 adrenergic receptor in Sprague-dawley rat to Ki for competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli in presence of PEA as substrate and AdoMet as co-substrate by Sigma-plot analysis | 21 | assay format | Scientific Literature | |||
5. | ALA4705018 | B | Non-competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as intercept inhibition constant in presence of 5 uM PEA as substrate and AdoMet as co-substrate by Sigma-plot analysis | Homo sapiens | 21 | assay format | Scientific Literature |