# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4689520 | Binding | Protac activity at VHL/AR in human LNCaP cells assessed as degradation of AR at 0.01 uM measured after 6 hrs by Western blot analysis relative to control | 6 | ALA4680362 | cell-based format | Scientific Literature | ||
2. | ALA4689521 | Binding | Protac activity at VHL/AR in human LNCaP cells assessed as degradation of AR at 0.1 uM measured after 6 hrs by Western blot analysis relative to control | 8 | ALA4680362 | cell-based format | Scientific Literature | ||
3. | ALA4689522 | Binding | Protac activity at VHL/AR in human LNCaP cells assessed as degradation of AR at 1 uM measured after 6 hrs by Western blot analysis relative to control | 10 | ALA4680362 | cell-based format | Scientific Literature | ||
4. | ALA5264642 | Binding | Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 0.01 uM incubated for 6 hrs by Western blot analysis (Rvb = 0%) | Homo sapiens | 18 | ALA5260842 | cell-based format | Scientific Literature | |
5. | ALA5264643 | Binding | Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 0.1 uM incubated for 6 hrs by Western blot analysis (Rvb = 0%) | Homo sapiens | 32 | ALA5260842 | cell-based format | Scientific Literature | |
6. | ALA5264644 | Binding | Protac activity at VHL/AR in AR-positive human LNCaP cells assessed as induction of androgen receptor degradation at 1 uM incubated for 6 hrs by Western blot analysis (Rvb = 0%) | Homo sapiens | 33 | ALA5260842 | cell-based format | Scientific Literature |